Enriching clinical studies with longitudinal real-world data

Connecting longitudinal real-world data (RWD) with clinical trial data can be a powerful method of contextualizing and enriching clinical trial results. Real-world evidence (RWE) gained from such data provides a deeper understanding of the patient’s diagnostic and treatment journey beyond the limited context of temporally bounded, site-based research, amplifying the power and precision of clinical studies. However, much RWD is unstructured and exists in fragmented data formats and sources, making it difficult to gather data and ensure that it is appropriate to the needs of a clinical study.

This case study explores how UBC partnered with the sponsor of a complex clinical trial to collect a rich, longitudinal real-world patient healthcare dataset spanning three years pre- and post-trial, using a robust data interoperability and evidence generation strategy. Read the case study to explore:

• An overview of the randomized clinical trial involved in the case study
• Insights that can be gained from linking longitudinal RWD to clinical study data
• Operationalization of patient tokenization to enable data linkage
• Effective data governance and privacy compliance.

Collaborative clinical evidence development

UBC’s evidence development services work with you to support your therapeutic program with reliable real-world evidence, driving deeper insights and meaningful outcomes. We look forward to learning how we can tailor an evidence generation plan to support your program’s goals. Learn more about Evidence Development Services or get in touch with us.