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Accelerating Evidence Synthesis without Compromising Scientific Rigor

Compressed HTA and JCA timelines are outpacing the fully manual literature review. See where AI can safely carry the work, where trained methodologists have to decide, and how to keep the difference auditable.

The problem

Evidence synthesis is being asked to move faster than it safely can

A rising tide of publications, shrinking submission windows, and cost pressure are making the fully manual literature review difficult to sustain. AI can screen tens of thousands of abstracts in minutes. But AI is a tool, not a scientist.

Without expert judgment at every critical step, AI-enabled reviews produce fast answers to the wrong questions.

The model

AI accelerates. Experts decide.

Expert-guided AI is neither fully manual nor fully automated. Technology carries the repetitive work; trained methodologists retain every decision that determines whether the evidence base survives peer review or HTA scrutiny.

AI accelerates

Repetitive, high-volume tasks

  • Title and abstract screening
  • Full-text screening
  • Data extraction
  • Risk of bias assessment
  • Report writing

Experts decide

Judgment that cannot be delegated

  • Study design
  • Clinical interpretation
  • Quality assurance
  • Scientific accountability

What it delivers

Validated across the stages that consume the most time

Screening is where compressed HTA and Joint Clinical Assessment timelines bite hardest, and where expert-guided AI returns the most time without loosening the standard.

95%

Reduction in title and abstract screening time

Achieved while maintaining high sensitivity for identifying relevant studies, with every screening decision reviewed by an expert before it enters the evidence base.

96%

Reduction in first-pass full-text screening time

Demonstrated high sensitivity and negative predictive value, supporting use as an efficient first-pass tool when coupled with expert review.

Validation results and full citations are in the white paper.

Authors

Prosper Maposa

Director, Business Development

Masoud Pourrahmat

Executive Director, Evidence Operations

Mir Sohail Fazeli

Senior Vice President, Strategic Solutions

Accelerate evidence synthesis with expert judgment at every decision point.

Get the full white paper for the eight-stage expert-guided workflow, the governance controls that keep AI-assisted reviews auditable, and where seven HTA bodies stand on AI in evidence generation.

Download the Full White Paper

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Bekki Bracken Brown

President & Chief Executive Officer

Bekki Bracken Brown serves as the President and CEO of UBC, guiding the company’s mission and values, including the improvement of access for patients to receive better outcomes. She oversees all aspects of UBC, such as operations, business growth strategy, sales and marketing, and acquisition support.

With over 20 years of industry experience, Ms. Brown brings knowledge from a successful career in senior management from her tenure at Quintiles, INC Research, and, most recently, with Syneos Health. She’s been a member of the North Carolina BIO Board of Directors since 2019. She is also a member of the Healthcare Businesswomen’s Association — Southeast Chapter and CHIEF, an organization that supports women executive leaders. Ms. Brown earned her bachelor’s degree at Duke University.